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Publications

Real-world biologics response and super-response in the International Severe Asthma Registry cohort (LUMINANT)

22 June 2024

Eve Denton, Mark Hew, Matthew Peters, John Upham, Lakmini Bulathsinhala, Trung N Tran, Neil Martin, Celine Bergeron, Mona Al-Ahmad, Alan Altraja, Désirée Larenas Linnemann, Ruth Murray, Carlos Andrés Celis-Preciado, Riyad Al-Lehebi, Manon Belhassen, Mohit Bhutani, Sinthia Bosnic-Anticevich, Arnaud Bourdin, Guy Brusselle, John Busby, Giorgio Walter Canonica, Enrico Heffler, Kenneth Chapman, Jeremy Charriot, George Christoff, Li Ping Chung, Li Ping, Borja G Cosio, Andréanne Côté, Richard Costello, Breda Cushen, James Fingleton, João A Fonseca, Peter G. Gibson, Liam Heaney, Erick Wan-Chun Huang, Takashi Iwanaga, David Jackson, Lauri Lehtimäki, Bassam Mahboub, Andrew Menzies-Gow, Patrick Mitchell, Nikolaos Papadopoulos, Andriana Papaioannou, Diahn-Warng Perng (Steve), Todor Popov, Celeste Porsbjerg, Chin Kook Rhee, Nicolas Roche, Mohsen Sadatsafavi, Sundeep Salvi, Johannes Martin Schmid, Chau-Chyun Sheu, Concetta Sirena, Carlos Arturo Torres-Duque, Laila Salameh, Pujan H. Patel, Charlotte Suppli Ulrik, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Jorge Máspero, Luis Perez de Llano, Paul E Peffler

Healthcare Resource Utilization Associated with Intermittent Oral Corticosteroid Prescribing Patterns in Asthma

21 June 2024

Trung N Tran, Heath Heatley, Arnaud Bourdin, Andrew Menzies-Gow, David Jackson, Ekaterina Maslova, Jatin Chapaneri, William Henley, Victoria Carter, Jeffrey Shi Kai Chan, Cono Ariti, John Haughney, David Price

Press Release
Study Slide Deck

Budesonide/glycopyrrolate/formoterol for the management of COPD in a UK primary care population: real-world use and early medication success

24 May 2024

Hana Müllerová, Jeffrey Shi Kai Chan, Heath Heatley, Victoria Carter, John Townend, Derek Skinner, Stefan Franzén, Jonathan Marshall, David Price

Pub Med
Press Release
Study Slide Deck

Exploring definitions and predictors of severe asthma clinical remission post-biologic in adults (FULL BEAM II)

8 May 2024

Ghislaine Scelo, Trung N Tran, Tham T. Le, Malin Fagerås, Borja G Cosio, Matthew Peters, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, Celine Bergeron, Leif Bjermer, Anne Sofie Bjerrum, Lakmini Bulathsinhala, John Busby, Diana Jimena Cano-Rosales, Giorgio Walter Canonica, Victoria Carter, Jeremy Charriot, George Christoff, Eve Denton, Delbert Dorscheid, João A Fonseca, Peter G. Gibson, Celine Goh, Liam Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, Rohit Katial, Piotr Kuna, Désirée Larenas Linnemann, Lauri Lehtimäki, Bassam Mahboub, Neil Martin, Hisako Matsumoto, Andrew Menzies-Gow, Nikolaos Papadopoulos, Todor Popov, Celeste Porsbjerg, Pujan H. Patel, Chin Kook Rhee, Mohsen Sadatsafavi, Camille Taillé, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, John Upham, Anna Von Bülow, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Luis Perez de Llano, Maria José Fernández-Sánchez, Ming-Ju Tsai, Paul E Peffler

Exploring definitions and predictors of response to biologics for severe asthma (FULL BEAM I)

8 May 2024

Ghislaine Scelo, Trung N Tran, Tham T. Le, Malin Fagerås, Delbert Dorscheid, John Busby, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, Aaron Beastall, Celine Bergeron, Leif Bjermer, Anne Sofie Bjerrum, Diana Jimena Cano-Rosales, Giorgio Walter Canonica, Victoria Carter, Jeremy Charriot, George Christoff, Borja G Cosio, Eve Denton, João A Fonseca, Peter G. Gibson, Celine Goh, Liam Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, Rohit Katial, Piotr Kuna, Désirée Larenas Linnemann, Lauri Lehtimäki, Bassam Mahboub, Neil Martin, Hisako Matsumoto, Andrew Menzies-Gow, Nikolaos Papadopoulos, Pujan H. Patel, Matthew Peters, Todor Popov, Celeste Porsbjerg, Chin Kook Rhee, Mohsen Sadatsafavi, Camille Taillé, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, John Upham, Anna Von Bülow, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Luis Perez de Llano, Maria José Fernández-Sánchez, Ming-Ju Tsai, Paul E Peffler

Association between pre-biologic T2-biomarker combinations and response to biologics in patients with severe asthma (IGNITE)

19 April 2024

Celeste Porsbjerg, John Townend, Celine Bergeron, George Christoff, Gregory P. Katsoulotos, Désirée Larenas Linnemann, Trung N Tran, Riyad Al-Lehebi, Sinthia Bosnic-Anticevich, John Busby, Mark Hew, Nikolaos Papadopoulos, Todor Popov, Chin Kook Rhee, Mohsen Sadatsafavi, Charlotte Suppli Ulrik, Mona Al-Ahmad, Alan Altraja, Aaron Beastall, Lakmini Bulathsinhala, Victoria Carter, Borja G Cosio, Kirsty Fletton, Susanne Hansen, Liam Heaney, Richard B. Hubbard, Piotr Kuna, Ruth Murray, Tatsuya Nagano, Laura Pini, Diana Jimena Cano-Rosales, Florence Schleich, Michael Wechsler, Rita Amaral, Arnaud Bourdin, Guy Brusselle, Wenjia Chen, Li Ping Chung, Li Ping, Eve Denton, João A Fonseca, Flavia Hoyte, David Jackson, Rohit Katial, Bruce J. Kirenga, Agnieszka Ławkiedraj, Lauri Lehtimäki, Mei Fong Liew, Bassam Mahboub, Neil Martin, Andrew Menzies-Gow, Pee Hwee Pang (Esther), Andriana Papaioannou, Pujan H. Patel, Matthew Peters, Luisa Ricciardi, Bellanid Rodríguez-Cáceres, Ivan Solarte, Tunn Ren Tay, Carlos Arturo Torres-Duque, Eileen Wang, Martina Zappa, John Abisheganaden, Karin Dahl Assing, Richard Costello, Peter G. Gibson, Enrico Heffler, Stefania Nicola, Diahn-Warng Perng (Steve), Francesca Puggioni, Sundeep Salvi, Chau-Chyun Sheu, Concetta Sirena, Camille Taillé, Tze Lee Tan, Leif Bjermer, Giorgio Walter Canonica, Takashi Iwanaga, Libardo Jiménez-Maldonado, Christian Taube, Luisa Brussino, David Price, Mariko Koh, Jorge Máspero, Kostas Kostikas, Luis Perez de Llano, Ming-Ju Tsai, Paul E Peffler

Trends in systemic glucocorticoid utilisation in the United Kingdom from 1990 to 2019: a population-based, serial cross-sectional analysis

15 March 2024

Andrew Menzies-Gow, Trung N Tran, Brooklyn Stanley, Victoria Carter, Josef S. Smolen, Arnaud Bourdin, Mark FitzGerald, Tim Raine, Jatin Chapaneri, Benjamin Emmanuel, David Jackson, David Price

International variation in severe exacerbation rates in patients with severe asthma

23 February 2024

Tae Yoon Lee, David Price, Chandra Prakash Yadav, Rupsa Roy, Laura Lim Huey Mien, Eileen Wang, Michael Wechsler, David Jackson, John Busby, Liam Heaney, Bassam Mahboub, Diahn-Warng Perng (Steve), Borja G Cosio, Riyad Al-Lehebi, Désirée Larenas Linnemann, Mona Al-Ahmad, Chin Kook Rhee, Takashi Iwanaga, Enrico Heffler, Giorgio Walter Canonica, Richard Costello, Nikolaos Papadopoulos, Andriana Papaioannou, Celeste Porsbjerg, Carlos Arturo Torres-Duque, George Christoff, Todor Popov, Mark Hew, Matthew Peters, Peter G. Gibson, Celine Bergeron, Saraid Cerda, Elvia Angelica Contreras Contreras, Wenjia Chen, Mohsen Sadatsafavi, Jorge Máspero, Luis Perez de Llano, Paul E Peffler

Reply to ‘‘Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry’’

7 February 2024

Wenjia Chen, Trung N Tran, Mohsen Sadatsafavi, Ruth Murray, Nigel Chong Boon Wong, Nasloon Ali, Cono Ariti, Lakmini Bulathsinhala, Esther Garcia Gil, Mark FitzGerald, Marianna Alacqua, Mona Al-Ahmad, Alan Altraja, Riyad Al-Lehebi, Mohit Bhutani, Leif Bjermer, Anne Sofie Bjerrum, Arnaud Bourdin, Anna Von Bülow, John Busby, Giorgio Walter Canonica, Victoria Carter, George Christoff, Borja G Cosio, Richard Costello, João A Fonseca, Peter G. Gibson, Liam Heaney, Enrico Heffler, Mark Hew, Ole Hilberg, Flavia Hoyte, Takashi Iwanaga, David Jackson, Rupert Jones, Piotr Kuna, Désirée Larenas Linnemann, Sverre Lehmann, Lauri Lehtimäki, Juntao Lyu, Bassam Mahboub, Andrew Menzies-Gow, Anthony Newell, Concetta Sirena, Nikolaos Papadopoulos, Andriana Papaioannou, Diahn-Warng Perng (Steve), Matthew Peters, Celeste Porsbjerg, Todor Popov, Chin Kook Rhee, Sundeep Salvi, Camille Taillé, Christian Taube, Carlos Arturo Torres-Duque, Charlotte Suppli Ulrik, Seung Won Ra, Eileen Wang, Michael Wechsler, David Price, Mariko Koh, Jorge Máspero, Kwang Ha Yoo, Luis Perez de Llano, Paul E Peffler

Abstract
Press Release
Study Slide Deck

The association between short-acting β2-agonist over-prescription, and patient-reported acquisition and use on asthma control and exacerbations: data from Australia

4 February 2024

David Price, Christine Jenkins, Rebecca Vella, Florian Heraud, Porsche Le Cheng, Ruth Murray, Sinthia Bosnic-Anticevich, Fabio Botini, Victoria Carter, Angelina Catanzariti, Joe Doan, Kirsty Fletton, Ata Kichkin, Thao Le, Chantal Le Lievre, Chi Ming Lau, Dominique Novic, John Pakos, Kanchanamala Ranasinghe, Alexander Roussos, Josephine Samuel-King, Anita Sharma, Deb Stewart, Bruce Willett, Eric Bateman, Kerry Hancock, Maarten Beekman

Association between T2-related co-morbidities and effectiveness of biologics in severe asthma

1 February 2024

Michael Wechsler, Ghislaine Scelo, Désirée Larenas Linnemann, Carlos Arturo Torres-Duque, Trung N Tran, Ruth Murray, Neil Martin, Andrew Menzies-Gow, Mark Hew, Matthew Peters, Peter G. Gibson, George Christoff, Todor Popov, Andréanne Côté, Celine Bergeron, Delbert Dorscheid, Mark FitzGerald, Kenneth Chapman, Louis Philippe Boulet, Mohit Bhutani, Mohsen Sadatsafavi, Libardo Jiménez-Maldonado, Mauricio Durán-Silva, Bellanid Rodriguez, Carlos Andrés Celis-Preciado, Diana Jimena Cano-Rosales, Ivan Solarte Rodriguez, Anna Von Bülow, Anne Sofie Bjerrum, Charlotte Suppli Ulrik, Karin Dahl Assing, Susanne Hansen, Alan Altraja, Arnaud Bourdin, Camille Taillé, Jeremy Charriot, Nicolas Roche, Andriana Papaioannou, Nikolaos Papadopoulos, Sundeep Salvi, Deirdre Long, Patrick Mitchell, Richard Costello, Concetta Sirena, Cristina Cardini, Enrico Heffler, Francesca Puggioni, Giorgio Walter Canonica, Giuseppe Guida, Takashi Iwanaga, Mona Al-Ahmad, Ulises García, Piotr Kuna, João A Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Borja G Cosio, Diahn-Warng Perng (Steve), Erick Wan-Chun Huang, Hao-Chien Wang, Bassam Mahboub, Laila Salameh, David Jackson, John Busby, Liam Heaney, Amanda Grippen Goddard, Eileen Wang, Flavia Hoyte, Nicholas Chapman, Rohit Katial, Victoria Carter, Lakmini Bulathsinhala, Cono Ariti, Juntao Lyu, Celeste Porsbjerg, David Price, Mariko Koh, Jorge Máspero, Kostas Kostikas, Linda M Rasmussen, Luis Perez de Llano, Maria José Fernández-Sánchez, Ming-Ju Tsai, Neva Eleangovan, Paul E Peffler, Patricia Parada

Longitudinal patterns of intermittent oral corticosteroid use for asthma in the UK

1 February 2024

Trung N Tran, Heath Heatley, Jennifer Rowell, Jeffrey Shi Kai Chan, Arnaud Bourdin, Jatin Chapaneri, Benjamin Emmanuel, Danny Gibson, David Jackson, Andrew Menzies-Gow, Ruth Murray, Derek Skinner, David Price

Abstract
Press Release
Study Slide Deck

Risk of pneumonia in patients with COPD initiating fixed dose inhaled corticosteroid (ICS) / long-acting bronchodilator (LABD) formulations containing extrafine beclometasone dipropionate versus patients initiating LABD without ICS

20 January 2024

David Price, William Henley, José Eduardo Delfini Cançado, Leonardo M. Fabbri, Huib AM Kerstjens, Alberto Papi, Nicolas Roche, Elif Şen, Dave Singh, Claus Vogelmeier, Elena Nudo, Victoria Carter, Derek Skinner, Rebecca Vella, Joan B Soriano, Maxim Kots, George Georges

Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma

25 December 2023

Ghislaine Scelo, Giorgio Walter Canonica, Wenjia Chen, William Henley, Désirée Larenas Linnemann, Matthew Peters, Trung N Tran, Charlotte Suppli Ulrik, Todor Popov, Mohsen Sadatsafavi, Mark Hew, Peter G. Gibson, George Christoff, Mark FitzGerald, Carlos Arturo Torres-Duque, Celeste Porsbjerg, Nikolaos Papadopoulos, Andriana Papaioannou, Enrico Heffler, Takashi Iwanaga, Mona Al-Ahmad, Piotr Kuna, João A Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Borja G Cosio, Diahn-Warng Perng (Steve), Bassam Mahboub, Andrew Menzies-Gow, David Jackson, John Busby, Liam Heaney, Pujan H. Patel, Eileen Wang, Michael Wechsler, Alan Altraja, Lauri Lehtimäki, Arnaud Bourdin, Leif Bjermer, Lakmini Bulathsinhala, Victoria Carter, Ruth Murray, Aaron Beastall, Eve Denton, David Price, Mariko Koh, Jorge Máspero, Luis Perez de Llano, Paul E Peffler

ImPact of comoRbidity In Severe asthMa patients (PRISM): association between T2-related co-morbidities and effectiveness of biologics in adult patients from the International Severe Asthma Registry

23 November 2023

Michael Wechsler, Ghislaine Scelo, Désirée Larenas Linnemann, Carlos Arturo Torres-Duque, Trung N Tran, Ruth Murray, Neil Martin, Andrew Menzies-Gow, Mark Hew, Matthew Peters, Peter G. Gibson, George Christoff, Todor Popov, Andréanne Côté, Celine Bergeron, Delbert Dorscheid, Mark FitzGerald, Kenneth Chapman, Louis Philippe Boulet, Mohit Bhutani, Mohsen Sadatsafavi, Libardo Jiménez-Maldonado, Mauricio Durán-Silva, Bellanid Rodriguez, Carlos Andrés Celis-Preciado, Diana Jimena Cano-Rosales, Ivan Solarte Rodriguez, Anna Von Bülow, Anne Sofie Bjerrum, Charlotte Suppli Ulrik, Karin Dahl Assing, Susanne Hansen, Alan Altraja, Arnaud Bourdin, Camille Taillé, Jeremy Charriot, Nicolas Roche, Andriana Papaioannou, Nikolaos Papadopoulos, Sundeep Salvi, Deirdre Long, Patrick Mitchell, Richard Costello, Concetta Sirena, Cristina Cardini, Enrico Heffler, Francesca Puggioni, Giorgio Walter Canonica, Giuseppe Guida, Takashi Iwanaga, Mona Al-Ahmad, Ulises García, Piotr Kuna, João A Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Borja G Cosio, Diahn-Warng Perng (Steve), Erick Wan-Chun Huang, Hao-Chien Wang, Bassam Mahboub, Laila Salameh, David Jackson, John Busby, Liam Heaney, Amanda Grippen Goddard, Eileen Wang, Flavia Hoyte, Nicholas Chapman, Rohit Katial, Victoria Carter, Lakmini Bulathsinhala, Cono Ariti, Juntao Lyu, Celeste Porsbjerg, David Price, Mariko Koh, Jorge Máspero, Kostas Kostikas, Linda M Rasmussen, Luis Perez de Llano, Maria José Fernández-Sánchez, Ming-Ju Tsai, Neva Eleangovan, Paul E Peffler, Patricia Parada

Press Release
Study Slide Deck

A long-term study of adverse outcomes associated with oral corticosteroid use in COPD

15 November 2023

Gary Tse, Benjamin Emmanuel, Cono Ariti, Mona Bafadhel, Alberto Papi, Victoria Carter, Jiandong Zhou, Derek Skinner, Xiao Xu, Hana Müllerová, David Price

Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry

25 August 2023

Ghislaine Scelo, Carlos Arturo Torres-Duque, Trung N Tran, Ruth Murray, Neil Martin, Andrew Menzies-Gow, Mark Hew, Matthew J Peters, Peter G. Gibson, George Christoff, Todor Popov, Andréanne Côté, Celine Bergeron, Delbert Dorscheid, Mark FitzGerald, Kenneth Chapman, Louis Philippe Boulet, Mohit Bhutani, Mohsen Sadatsafavi, Libardo Jiménez-Maldonado, Mauricio Durán-Silva, Bellanid Rodriguez, Carlos Andrés Celis-Preciado, Diana Jimena Cano-Rosales, Ivan Solarte, Anna Von Bülow, Anne Sofie Bjerrum, Charlotte Suppli Ulrik, Karin Dahl Assing, Susanne Hansen, Alan Altraja, Arnaud Bourdin, Camille Taillé, Jeremy Charriot, Nicolas Roche, Andriana Papaioannou, Nikolaos Papadopoulos, Sundeep Salvi, Deirdre Long, Patrick Mitchell, Richard Costello, Concetta Sirena, Cristina Cardini, Enrico Heffler, Francesca Puggioni, Giorgio Walter Canonica, Giuseppe Guida, Takashi Iwanaga, Mona Al-Ahmad, Désirée Larenas Linnemann, Ulises García, Piotr Kuna, João A Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Borja G Cosio, Diahn-Warng Perng (Steve), Erick Wan-Chun Huang, Hao-Chien Wang, Bassam Mahboub, Laila Salameh, David Jackson, John Busby, Liam Heaney, Amanda Grippen Goddard, Eileen Wang, Flavia Hoyte, Michael Wechsler, Nicholas Chapman, Rohit Katial, Victoria Carter, Lakmini Bulathsinhala, Cono Ariti, Juntao Lyu, David Price, Celeste Porsbjerg, Mariko Koh, Jorge Máspero, Kostas Kostikas, Linda M Rasmussen, Luis Perez de Llano, Maria José Fernández-Sánchez, Ming-Ju Tsai, Neva Eleangovan, Paul E Peffler, Patricia Parada

Patterns of Care in the Management of High-Risk COPD in the US (2011-2019): An Observational Study for the CONQUEST Quality Improvement Program

31 July 2023

Margee Kerr, Yasir Tarabichi, Alexander Evans, Douglas Mapel, Wilson Pace, Victoria Carter, Amy Couper, M. Bradley Drummond, Norbert Feigler, Alex Federman, Hitesh Gandhi, Nicola A. Hanania, Alan Kaplan, Maja Kruszyk, Marije van Melle, Hana Müllerová, Ruth Murray, Jill Ohar, Michael Pollack, Rachel Pullen, Dennis Williams, Juan Wisnivesky, MeiLan K Han, Catherine Meldrum, David Price, Kostas Kostikas

Abstract
Study Slide Deck

Adult severe asthma registries: a global and growing inventory

28 July 2023

Breda Cushen, Trung N Tran, Neil Martin, Ruth Murray, Thendral Uthaman, Celine Goh, Rebecca Vella, Lakmini Bulathsinhala, Matthew Peters, Florence Schleich, Paulo Pitrez, George Christoff, Mohsen Sadsatsafavi, Carlos Arturo Torres-Duque, Celeste Porsbjerg, Alan Altraja, Lauri Lehtimäki, Arnaud Bourdin, Christian Taube, Nikolaos Papadopoulos, Csoma Zsuzsanna, Unnur Steina Björnsdóttir, Sundeep Salvi, Enrico Heffler, Takashi Iwanaga, Mona Al-Ahmad, Désirée Larenas Linnemann, Job F.M. van Boven, PharmD, Bernt Bøgvald Aarli, Piotr Kuna, Cláudia Chaves Loureiro, Riyad Al-Lehebi, Jae Ha Lee, Nuria Marina, Leif Bjermer, Chau-Chyun Sheu, Bassam Mahboub, John Busby, Andrew Menzies-Gow, Eileen Wang, David Price, Mariko Koh, Jorge Máspero, Neva Eleangovan

Data Resource Profile: Optimum Patient Care Research Database (OPCRD)​

27 April 2023

Anita Lynam, Charlotte Curtis, Brooklyn Stanley, Heath Heatley, Chloe Worthington, Emma-Jane Roberts, Chris Price, Victoria Carter, John Dennis, Andrew McGovern, David Price

Abstract
Press Release
Study Slide Deck
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